I did actually start a Saw inspired story, where a bunch of guys are all challenged to complete challenges that turn them all into various gay pervs, but I never finished it. I’ll keep your idea in mind, however.
How about a guy gets kidnapped and trapped in a abandoned warehouse a la Saw. To get out of each room, he loses a bit of himself, his big cock, his muscles, his cleanliness, his heterosexuality, his intelligence. In the last room he almost gets away, but ends up becoming a dog for his captor.
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Bracken's Corner 